Biopolymers and cell. 2003; 19 (3): 238 - 241

The influence of teichoic acid of Staphylococcus aureus Wood 46 on cylolytic activity of natural killer cells

N. V. Senchilo, S. V. Olishevskyy, V. K. Pozur

The influence of different concentrations of teichoic acid (TA) Staphylococcus aureus Wood 46 on NK-mediated lysis of tumor cells of Erlich carcinoma has been investigated. Low and moderate TA concentrations have been shown to enhance the NK-activity, whereas high concentrations are suppressive for NK-mediated tumor lysis. The simultaneous usage of TA and phorbolmyrystateacetate causes dose-dependent inhibition with inverse correlation.