Biopolymers and cell. 2003; 19 (2): 140 - 150

Comparative analysis of primary and secondary structures of carlaviruses' capsid proteins

T. Yu. Tkachenko, S. S. Viter, Yu. L. Radavsky

The primary and secondary structures of 23 carlaviruses' capsid proteins have been analysed. As a result of the primary structure analysis by multiple alignment seven motifs have been established, three of them being specific for the carlaviruses' capsid proteins. The secondary structure analysis by means of multiple comparison has shown a high degree of secondary structure conservatism in the core and C-terminal regions, and considerable variability in the N-terminus. A general scheme for the secondary structure of the carlaviruses' capsid proteins has been proposed, on the base of multiple comparison results.