Biopolymers and cell. 2002; 18 (5): 411 - 416

Radiogenic alterations of RNA and DNA in rat spleen under various conditions of Irradiation

L. G. Petryna

The content of nucleic acids in the Vistar line rat spleen has been found to change after a total single y-irradiation at 1.0, 5.0 and 9.0 Gy doses of 0.001, 0.01, 0.1 and 1.0 Gy/min dose power. The degree of these alterations, their direction and extent of mani¬festation depend on the dose of irradiation. The experimental data show that the decrease in irradiation intensity prolongs the time of reaching an extreme point and decreases the effect level in this point. The correlation between the RNA and DNA content changes in animals caused by their irradiation has been discussed.