Biopolymers and cell. 2002; 18 (2): 114 - 116

Mass spectrometry (252Cf-PDMS) study of aminoglycoside antibiotics interaction with nucleic acid components

KALINKEVICH A. N., PILIPENKO V. V., KALINICHENKO T. G., SUKHODUB L. F.

Relative affinity of the aminoglycoside antibiotic streptomycine to nucleosides — adenosine, uridine, guanosine, cytidine was studied by the plasma desorption mass spectrometry ( Cf-PDMS). It has been shown that the affinity decreases in the row Urd > Ado > Cyd >Guo.