Biopolymers and cell. 2000; 16 (5): 436 - 442

The combinatorial approach to the synthesis of new 6-aza analogs of the uracil and thymine

S. M. Tomachynski, S. S. Ognyanik, S. M. Yarmoluk

A new one stage method of the synthesis of 3-hydrazino-2H-l,2,4-tliriazin-5-one and 3-hydrazino-6-methyl-2H-l,2,4-thriazin-5-one has been designed in order to create the combinatorial libraries. The series of new 2-(N'-benzylydene-hydrazino)-6-asawacils and 2-(N'-benzylydene-hydrazino)-6-azathymins have been obtained.