Biopolymers and cell. 2000; 16 (1): 40 - 45

Comparative study of troponin complex immunoreactivity at dilated and ischemic cardiomyopathies

L. L. Sidorik, O. M. Fedorkova, D. V. Ryabenko, V. I. Bobyk, V. M. Danilova, V. S. Tregubov, G. Kh. Matsuka

The features of the immune reactions against troponin complex isolated from human ventricular myocardium in sera of patients with dilated cardiomyopathy (DCM) and patients with cardio-megaly of ischemic origin (ICM) have been investigated. The results have shown that sera antibodies level against troponin complex antigenes were considerably higher in patients with DCM. The most pronounced immunogenisity of troponin complex isolated from DCM patient myocardium has been shown.