Biopolymers and cell. 1999; 15 (3): 207 - 212

Search for HIV and herpes Inhibitors among the derivatives of polyhedranee and pyridinecarboxylic acid

G. /. Danilenko, S. L. Rybalko, Ju. M. Maximov, N. I. Sharykina, S. T. Diadiun, V. G. Arkadiev, V. P. Danilenko, N. V. Nestftmva, S. V. Guzhova, T. A. Bukhtiarova, K M. O\-ruisky, O. Yu. Zakhartsev, T. F. Gritsak, E. V, Maksimenok, N. O. Vri+chanu.

It was found that an adamantane derivative (5) inhibits HIV replication as azidothymidin but has immuitostimu/ative properties. The derivatives of isonicotinic acid (2) anil norbornane (4) manifest both antiherpes and immunostimu/ative activity.