Biopolymers and cell. 1999; 15 (2): 143 - 148

Structural and functional peculiarities of neural cell adhesion proteins of immunoglobulin family

D. D. Zhernossekov

Cell adhesion molecules (CAMs) of immunoglobulin family (Ig family) present a wide group of the proteins which provide cell-cell adhesion during morphogenesis and synaptogenesis. There is a lot of data concerning the structure and function of the neural CAMs. In the present review both main principles using for classification CAMs Ig family and the molecular-genetic approach to investigate these proteins have been discussed. There « a unity of the domain structure at CAMs Ig family, which have been isolated from different species. The relation between structural peculiarities and specific functions of CAMs have been discussed.