Biopolymers and cell. 1998; 14 (6): 553 - 558

The high scale screening of confounds of the series of isoflavonoids and 4-phenylcoumarins with the use of microorganisms

A. M. Zhyvoloup, S. M. YarmoLuk, M. M. G-arazd, Y. L. Garazd, V. V. Sliylm, A. S. Ogorodniych.uk, V. P. KMtya

In order to investigate antimicrobial activity of more then 300 compounds of the series of isoflavonoids and 4-phenylcoumarins Salmonella typhimurium LT.2, Escherichia coll and Candida albi-cans were used. Two structural chemical fragments 7-( J-Rr2-R2-J-on-ethyl)-O-4-phenylcou.marin and 2-R4-3-Rs-6-R-r8-R'r7-R{O-diromone possessing antibactericidal and anticandidal effects were determined.