Biopolymers and cell. 1998; 14 (5): 389 - 395

The mutation processes resulting to cancer: the role of ALL* repeats in genetic instability

L. P. Shvachko

ALV repeats is numerous the family of mobile genetic elements or retroelements of human genome. This elements take part in the activity recombination events and often participating in the deletion formation, tram locations and fusion genes in cancer. It's shown the ALV transposition and incrising of the ALU transcriptions in cancer as leukemia. ALU repeats have been relationship to genetic rear¬rangements in number human inheriditary diseases too. At last time it's have been observation about the ability of ALV retroelements to modulate the gene expression. It's assumed the role of ALU elements could be important in the search of the early genetic targets of tumorogenesis.