Biopolymers and cell. 1996; 12 (6): 82 - 86
The tetrahydrofuranylic derivatives of Ch substituted 3,5-dioxo- and 3,5-thioxo-1,2,4-triazines as a structural analogs of azapyrimidine nucleosides
L. I. Palchikovskaya, 1. V. Alexeeva, A. S. Shalamay
Influence of C^-aminoalkyl-, Ch-mercaptoalkyl-substitutes of 3,5-dioxo- and 3,5-thioxo-derivatives 1,2,4-triazines on the process of tetrahydrofuranylation has been studied. This study was conducted in the conditions, similar to the one-step reactionof nucleic bases glycosylation. We discovered significant depenŽdence of the regiospecifity of this reaction from electronic nature of substitutes in the 6-position.