Biopolymers and cell. 1996; 12 (2): 20 - 23

In vitro specific cleavage of HIV-1 faf-RNA by catalytically active polyribonucleotide, ribozyme

L. N. Buryanovsky, A. D. Schved

The hammerhead type ribozyme-mediated cleavage oftat-RNA of human immunodeficiency virus type 1 data are presented. The ribozyme activity was appeared in magnesium-dependent manner at moderate temperature in the presence ofmonovalent cations and/or potyamines.