Biopolymers and cell. 1996; 12 (1): 16 - 28

Caldesmon and calponin — the thin filamentassociated proteins of smooth muscle: structure and mechanisms of functioning

V. M. Danilova, N. V. Kulikova

The structure and properties of two novel smooth muscle regulatory proteins associated with thin filament arereviewed. A detailed description of the «heavy» caldes man isofarm and of the localization of ca Ides man interaction sites withactin, calmodulin, tropomyosin and myosin are given. Current conceptions concern¬ing the mechanism ofcaldcsmon and calponin function during regulation of myosin interaction with actin are considered.