Biopolymers and cell. 1995; 11 (2): 52 - 56

STUDY OF CHROMOSOME-PLASMIDIC DETERMINATION OF ANTIBIOTIC-RESISTANCE IN STRAINS OF CAMPYLOBACTER GENUS

D. L. Kirik, E. E. Shablovskaya, L. N. Buryanovsky, N. M. Krotevetskaya, V. I. Kikot

Investigations on studying of chomosome-plasmidic determination characteristics of antibiotic-resistance in strains of Campylobacter isolated from different sources are presented. An analysis of antibioticogramms isolated Campylobacter strains has showed that 12 from them (31,6 %) possessed a great number of medical resistance. A plasmid presence of determinated antibiotic-resistance in 7 from 38 examined cultures (18,4 %) was set up. The treatment with ethidium bromide was being conducted to change of phenotypical properties of plasmid-containing strains. After elimination of plasmids (MW is approximately 40—70 MD) the strains resistance to tetracycline and erythromycine have been lost but a mowing of plasmids MM approximately 1,5—6 MD — kanamycine. Plasmid character of a great number of Campylobacter resistance can be editional criteria of epidemic strain's danger