Biopolymers and cell. 1994. Volume 10. № 1. 100 - 103

L. B. Bondarenko, R. I. Yahimovich

CHICKENS CARTILAGE TYPE II COLLAGENS ISOELECTRICAL FOCUSING WITH DIFFERENT RATION'S PROVIDING WITH Ca AND VITAMIN D ANALOGS

Summary

    Influence of rickets, Ca from diet and different doses of vitamin D analogs on cartilage type II 'collagen surface charge was studied in experiments on chickens. Chicken cartilage collagen pi were established. It was shown that rachitic type II collagen molecule had more negative charge then normal one. This effect wasn't compensated with Ca load at the absence of vitamin D3. Influences of vitamin D3 hydroxy-analogs and maximal dose of 3|3-fluorovitamin D3 were analogous to its effect.