Biopolymers and cell. 1993. Volume 9. № 5. 82 - 88

AVDEEVA L. V., LUKACH I. G., VOICEHOVSKY V. G., SELNIKOVA O. P., POLYSCHUK E. I., CHERNYAK L. N.

Peculiarities of Development of Tolerant to Cefamesine Klebsiella Stamms

Summary

    In chambers for microorganisms flowing cultivation morphological alterations of Klebsiella's cells in presence of different cefomisine's concentrations were discovered with the using of. Recived results testify to varions sensitivity of Klebsiella's to the cefomisine which was taken in account 3—5 hours later already. In addition Klebsiella's tolerance strains (MBC/MIC^32) capable to survive in high antibiotic's concentrations in L-forms which reverse to original forms (ones) during the change of antibiotics medium for nutritions one were established among clinical isolates. It is supposed, that tolerance strains are potentially dangererous with hospital-aquired infections.