Biopolymers and cell. 1992. Volume 8. № 6. 30 - 34

MASHANAUSKAS T. K., IVANOV L. L., RODOVICHIUS H. A., LUKOSHEVICHIUS L. J., PRASHKEVICHIUS A. K.

Protein Biosynthesis in Cell-Free Systems From Rabbit Liver Under Experimental Myocardial Ischemia

Summary

    The level of protein biosynthesis in cell-free systems from rabbit li¬ver was studied both in norm and 12 h after experimental rnyocardial ischemia (EMI). The results demonstrate that the rise in the level of [14C]-leucine incorporation into translational product in cell-free system under EMI is related to the increase of aminoacyl-tRNA synthetase activity. Electrophoretical analysis of the translational products with subsequent fluorography has revealed redistribution in the spectrum of the pro¬teins synthesized in cell-free system under EMI.