Biopolymers and cell. 1992. Volume 8. № 5. 31 - 35

KARABUT L. V., SEREYSKAYA A. A.

The Peculiarities of Thrombin Binding Sites Structure. Putative Mechanisms of Interaction With Highmolecular and Small Substrates

Summary

    The peculiarities of active site structure and second binding site structure of thrombin is revealed. Alternative mechanisms of thrombin interaction with highmolecular or lowmolecular substrates are supposed. Also it is shown, putative function of the additional center ot thrombin in productive enzyme-substrate complex formation.