Biopolymers and cell. 1991. Volume 7. № 5. 103 - 107

LANDAU S. M., TICHONOV A. V., VARZANOVA I. S., ZHAROVA L. G.

Determination of Replicative Activity of Recombinant Plasmids Carrying SV40 Eukaryotic Regulatory Region in Mammalian Cell Cultures

Summary

    The recombinant plasmids replication in mammalian cell cultures has been employed as a method for estimating the functional activity of SV40 eukaryotic regulatory region. It was shown that recombinant plasmids examined replicate in mammalian cell cultures and therefore possess functional active SV40 regulatory region. This method can be used for the purposes of gene therapy.