Biopolymers and cell. 1991. Volume 7. № 3. 35 - 38

DOLZHANSKAYA M. T., TODOROVA M. T., SCHWARZMAN A. L.

Obtaining of the Anti-Sense cDNA Construction of human Low-Density Lipoprotein Receptor

Summary

    The anti-sense cDNA construction of human low-density lipoprotein receptor (rLDL) was obtained. It includes the 5'-terminal fragment of cDNA rLDL and the murine metal-lothionein gene promoter. The construction may be used to obtain transgenic animals that are deficient of rLDL.