Biopolymers and cell. 1991. Volume 7. № 2. 103 - 109

FROLKIS V. V., KORDIUM V. A., BOGATSKAYA L. N., NOVIKOVA S. N., SHULZHENKO V. N., KOSTETSKY I E., MOZZHUKHINA T. G., POTAPENKO R. I., SABKO V. E., PARAMONOVA G. I. .

Age Peculiarities of Human apoAl Gene Implantation Effect on the Development of Dislipoproteidemias in the Experimental Animals

Summary

    After introduction of human apo Al gene as in an expression vector into liver of adult and old rats we could reveal this human protein in the serum of the animals. Changes in HDL, HDL3 and HDL2 subfamilies its protein and lipid contents could be observed also. A higher apo Al gene expression was observed in adult young animals while old animals, showed greater differences in protein and lipid contents.