Biopolymers and cell. 1990. Volume 6. 6. 63 - 68

 

V. V. Schmatchenko, A. B. Berezhnev

 

MAPPING DNA ATTACHMENT SITES ON NUCLEAR FRAME BY GRAPHIC REPRESENTATION OF LONG DNA SEQUENCES

 

Summary

 

    Characteristic (S-form) curves corresponding to nuclear matrix association regions have been revealed by graphically represented DNA sequences. The curves reflect AT and GC distribution along the sequence length. The method is applicable for mapping DNA attach¬ment sites on nuclear frame. Functionally identical nonhomologous DNA regions in long sequences can be detected which is impossible using other computer-assisted methods of nucleotide sequence analysis.