Biopolymers and cell. 1990. Volume 6. 6. 31 - 36

 

A. P. Gultyaev, Yu. N. Monakov

 

THE METHOD FOR RNA SECONDARY STRUCTURE CONSTRUCTION ON THE BASIS OF SELF-ORGANIZATION PRINCIPLES

 

Summary

 

    The method for computer calculation of RNA secondary structure is described. The al¬gorithm is based on successive formation of helices in the RNA self-organization pro¬cess with the generation of random structure sets by the Monte-Carlo mehtod. This way permits constructing RNA secondary structures for rather long sequences (up to 5000 nucleotides) by means of the personal computer without using large memory volumes.