Biopolymers and cell. 1989. Volume 5. № 6. 83 - 86

V. I. Prima, T. A. Clochko, M. Yu. Obolenskaya, P. L. Ivanov, A. P. Ryskov, 0. M. Platonov

SYNCHRONOUS CHANGES OF C-FOS RNA AND B2+mRNAx CONCENTRATIONS DURING PREREPLICATIVE PERIOD IN REGENERATING RAT LIVER

Summary

    The relative abundance of c-fos RNA and mR'NA containing repetitive sequence B2 (B2+mRNAx) has been studied in nuclear and poly(A)+ cytoplasmic RNA of regenerating liver during Oil2 h after partial hepatectomy. The data of DNA-RlN'A hybridization reveal that c-fos transcripts are mainly localized in nucleus and their relative abundance is maximal 0.5 and \'.2 h after operation. On the contrary B'2+rrvRNAx is mainly localized in poly (A) + cytoplasmic R>NA and its concentration is the lowest in the same periods after operation. The differences in the investigated gene expression are possibly connected with functional peculiarities of terminal products of both genes.