Biopolymers and cell. 1989. Volume 5. № 5. 75 - 80

S. V. Shagun, A. P. Koval, V. M. Kavsan

DETERMINATION OF 5'- AND 3'-NUCLEOTIDE SEQUENCE OF MAV-1 POL GENE

Summary

    The nucleotide sequences of 5'-, and 3'-terminal parts of MAV-1 pol gene are determined. 94.6 % homology between RSV and MAV-1 reverse transcriptase genes has been established. Only 15 base pairs from the sequencing regions differ from the corresponding RSV sequence. Six of them determine amino acids substitutions. The asparagin appearance in position 15 of the MAV-1 reserse transcriptase is in accordance with the previous data on protein. This observation may serve as an evidence, that the MAV-1 pol gene codes for reverse transcriptase of AMV-complex.