Biopolymers and cell. 1989. Volume 5. № 2. 43 - 47

N. S. Neznanov, I. V. Makarova, I. A. Kramerova, K. G. Gazaryan

CLONING OF HUMAN a,-ANTITRYPSIN GENE AND POSSIBLE ASPECTS OF ITS UTILIZATION

Summary

    The human arantitrypsin gene has been cloned. A cDNA molecule, containing almost the whole coding sequence is isolated. Nucleotide sequence is determined for the regulatory region of aiAT gene, responsible for its expression in the liver. The possibility to use cloned genes for the gene therapy of some diseases is discussed.