Biopolymers and cell. 1988. Volume 4. № 5. 272 - 274

B. V. Shestopalov

SIMILARITY OF DNA-RECOGNIZING STRUCTURES OF THE COORDINATED TRANSCRIPTION ACTIVATOR OF YEAST AMINO ACID BIOSYNTHESIS ENZYMES GENES, YEAST CELLS DIFFERENTIATION REGULATORS, DEVELOPMENT AND MORPHOGENESIS REGULATORS

Summary

    Basing on the data obtained by the method of necessary stereochemical requirements of the DNA-recognizing structure helix-turn-helix existence and the available data from literature a conclusion is made that 1) GCN4 protein, probably, recognizes DNA using DNA-recognizing structure helix-turn-helix, localized in the amino acid sequence segment 256-278 and 2) DNA-recognizing structure of GCN4 protein is similar to those of MATal and MATaS proteins, and homoeodomain-containing proteins.