Biopolymers and cell. 1988. Volume 4. № 4. 220 - 222

V. F. Zarytova, E. M. Ivanovo, S. N. Yarmolyuk, I. V. Alekseeva

SYNTHESIS OF ARGININE-CONTAINING OLIGONUCLEOTIDE-(5' — N)-PEPTIDES

Summary

    A new method for synthesis of oligonucleotide-peptides of phosphoamide type with the use of a mixture of triphenylphosphine, dipyridyldisulphide and N-methylimidazole is suggested. This approach was applied for synthesizing and isolating d(CCCC)-5'-P-Pro-Arg-Val-OMe.