Biopolymers and cell. 1986. Volume 2. № 4. 185 - 189

G. Zh. Yusupova (Tnalina), N. V. Belitsina, A. S. Spirin

TEMPLATE-FREE RIBOSOMAL SYNTHESIS OF POLYPEPTIDES FROM AMINOACYL-tRNAs : POLYPHENYLALANINE SYNTHESIS FROM PHENYLALANYL-tRNA^Lys

Summary

    Misacylated phenylalanyl-tRNA^Lys, similar to lysyl-tRNA^Lys, but not phenylalanyl-tRNA^Phe, is able to serve as a substrate for ribosomal synthesis of polypeptides (poly-phenylalanine and polylysine, respectively) in the absence of a template polynucleotide (poly(A)). Thus, it is the structure of tRNA that determines the ability of the amino-acyl-tRNA^Lys to participate in the peptide elongation on ribosomes without codon-anti-codon interactions.

Summary in Russian